CA125, progesterone & β-hCG in prediction of first trimester abortion

Maternal serum levels of interleukin-6 and β-hCG in women with hyperemesis gravidarum in the first trimester of pregnancy

Background and Objective: Hyperemesis gravidarum (HG) is defined as vomiting sufficiently severe to produce weight loss, dehydration, electrolyte abnormalities. Interleukin-6 (IL-6), a pro-inflammatory and trophoblast-derived cytokine has ability to induce trophoblasts to secrete human chorionic gonadotropin (hCG). The purpose of our study was to assay the level of IL-6 and β-hCG in serum of pr...

Serum Angiopoietin-2 and β-hCG as Predictors of Prolonged Uterine Bleeding after Medical Abortion in the First Trimester

OBJECTIVE The combination of mifepristone and misoprostol is an established method for induction of early first trimester abortion, but there is no consensus about the best evaluation of treatment outcome. We evaluate serum Angiopoietin-2 (Ang-2) and β human chorionic gonadotropin (β-hCG) in women who had undergone a medical abortion as markers of prolonged uterine bleeding (PUB). METHODS Pro...

Abortion in the first trimester.

Placenta Percreta Resulting in Incomplete Spontaneous Abortion in First Trimester

Comparative expression of hCG β-genes in human trophoblast from early and late first-trimester placentas.

Human chorionic gonadotropin (hCG) displays a major role in pregnancy initiation and progression and is involved in trophoblast differentiation and fusion. However, the site and the type of dimeric hCG production during the first trimester of pregnancy is poorly known. At that time, trophoblastic plugs present in the uterine arteries disappear, allowing unrestricted flow of maternal blood to th...